Diagnosis of a Critical Respiratory Illness from Human Metapneumovirus Using a Pan-Viral Microarray
Chiu, Alizadeh, Rouskin, Merker, Yeh, Yagi, Schnurr, Patterson, Ganem, DerisiJ Clin Micro 2007Abstract:
A pan-viral DNA microarray (Virochip) was used to detect a human metapneumovirus (hMPV) strain associated with a critical respiratory tract infection in an elderly adult with chronic lymphocytic leukemia. This infection had previously eluded diagnosis despite extensive microbiological testing for possible etiologic agents. The patient's hMPV strain did not grow in viral culture, and only one of five specific RT-PCR assays for hMPV was positive.