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2019-07-03 [ PDF ]
Exploratory proteomic analysis implicates thealternative complement cascade in primary CNS vasculitis
Caleigh Mandel-Brehm, PhD,* Hanna Retallack, AB,* Giselle M. Knudsen, PhD, Alex Yamana, BS,Rula A. Hajj-Ali, MD, Leonard H. Calabrese, DO, Tarik Tihan, MD, PhD, Hannah A. Sample, BS,Kelsey C. Zorn, MHS, Mark P. Gorman, MD, Jennifer Madan Cohen, MD, Antoine G. Sreih, MD,Jacqueline F. Marcus, MD, S. Andrew Josephson, MD, Vanja C. Douglas, MD, Jeffrey M. Gelfand, MD,Michael R. Wilson, MD, and Joseph L. DeRisi, PhD

Neurology, 2019

Abstract: To identify molecular correlates of primary angiitis of the CNS (PACNS) through proteomic analysis of CSF from a biopsy-proven patient cohort