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|  Ball Python Nidovirus: a Candidate Etiologic Agent for Severe
Respiratory Disease in Python regius
Ball pythons are popular pets because of their diverse coloration, generally nonaggressive behavior, and relatively
small size. Since the 1990s, veterinarians have been aware of an infectious respiratory disease of unknown cause in ball pythons
that can be fatal. We used unbiased shotgun sequencing to discover a novel virus in the order Nidovirales that was present in
cases but not controls. While nidoviruses are known to infect a variety of animals, this is the first report of a nidovirus recovered
from any reptile. This report will enable diagnostics that will assist in determining the role of this virus in the causation of disease,
which would allow control of the disease in zoos and private collections. Given its evolutionary divergence from known
nidoviruses and its unique host, the study of reptile nidoviruses may further our understanding of related diseases and the viruses
that cause them in humans and other animals.
Photo credit: Christina Wozniak.
[ Read the full open-access article at the mBio website ] |
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