Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR T cell therapies in autoimmunity J Clin Invest 2024
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Molecular mimicry in multisystem inflammatory syndrome in children Nature Portfolio, 2024
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Phage Immunoprecipitation-Sequencing Reveals CDHR5 Autoantibodies in Select Patients With Interstitial Lung Disease American College of Rheumatology, 2024
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Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency Sci Tran Med 2024
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An autoantibody signature predictive for multiple sclerosis Nat Med 2024
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Field assessment of BinaxNOW antigen tests as COVID-19 treatment entry point at a community testing site in San Francisco during evolving omicron surges PLOS One, 2023
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Antibodies to repeat-containing antigens in Plasmodium falciparum are exposure-dependent and short-lived in children in natural malaria infections eLife, 2023
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Dual ankyrinG and subpial autoantibodies in a man with well-controlled HIV infection with steroid-responsive meningoencephalitis: A case report Frontiers, 2023
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Successful Treatment of Balamuthia mandrillaris Granulomatous Amebic Encephalitis with Nitroxoline Emerging Infectious Diseases, 2023
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Prolonged silent carriage, genomic virulence potential and transmission between staff and patients characterize a neonatal intensive care unit (NICU) outbreak of methicillin-resistant Staphylococcus aureus (MRSA) Cambridge University Press, 2023
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Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps Science Direct, 2023
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Pathobiological signatures of dysbiotic lung injury in pediatric patients undergoing stem cell transplantation Nature Portfolio, 2024
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| Ball Python Nidovirus: a Candidate Etiologic Agent for Severe
Respiratory Disease in Python regius
Ball pythons are popular pets because of their diverse coloration, generally nonaggressive behavior, and relatively
small size. Since the 1990s, veterinarians have been aware of an infectious respiratory disease of unknown cause in ball pythons
that can be fatal. We used unbiased shotgun sequencing to discover a novel virus in the order Nidovirales that was present in
cases but not controls. While nidoviruses are known to infect a variety of animals, this is the first report of a nidovirus recovered
from any reptile. This report will enable diagnostics that will assist in determining the role of this virus in the causation of disease,
which would allow control of the disease in zoos and private collections. Given its evolutionary divergence from known
nidoviruses and its unique host, the study of reptile nidoviruses may further our understanding of related diseases and the viruses
that cause them in humans and other animals.
Photo credit: Christina Wozniak.
[ Read the full open-access article at the mBio website ] |
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